letrozole, severely impaired hepatic function, uncontrolled hypertension and thromboembolism. You usually take letrozole once a day – try. Maximum dosage. Letrozole Bluefish contains an active substance called letrozole. #lezraexcelta. Letrozole is a medication that treats breast cancer and infertility. 3%) had hypoestrogenic. sudden, severe weakness or numbness in the arm or leg. Timed intercourse is essentially, just like it sounds; a couple engages in intercourse a few days before ovulation which allows the sperm just enough time to swim through the uterus and into the. Some studies have found an increased risk of certain cancers if Clomid is used more than six times without a pregnancy success, and Clomid can also thin the uterine lining Therefore, if Clomid or Femara doesn’t work after. 21. 60 for placebo and letrozole, respectively; P = . It is also used off-label for the treatment of infertility, idiopathic short stature in. severe, sudden headache. What Femar is and how it works. In some cases, LETROZOLE may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling. Letrozole is a medication used in the treatment of certain breast cancers. Many clinics now prescribe Letrozole in place of Clomiphene Citrate (Clomid), which has been the standard. 2. Cycles that include gonadotropins have 8 - 10% live birth rates, 8 - 30% multiples-per-pregnancy, and cost $4,000 in the U. Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Modify Therapy/Monitor Closely. Estrogen use with letrozole: use other options for conditions in which estrogen is indicated. Lezra is used to treat postmenopausal breast cancer. If you're a patient at MSK and you need to reach a provider after 5 p. Sequential endocrine therapy with tamoxifen for 2–3 years followed by letrozole for 5. com on May 25, 2023. 2) First and second-line treatment of. This helps to reduce the risk of breast cancer coming back. Those receiving letrozole had a significantly greater decrease in total hip BMD (percentage change in T score, mean −0. 2 Use of Lez-T and Food: The tablet can be taken with or without food. Still, there was a similar incidence between the letrozole and the control groups,. By decreasing the amount of estrogen in the body, letrozole can slow or stop. We aimed to determine whether poor/sub-optimal responders might benefit from Letrozole co-treatment throughout the entire stimulation course. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. Letrozole, an aromatase inhibitor, improves seminal parameters and hormonal profile in aged endangered Markhoz bucks. 1, 5, 9, 10 It is a third generation aromatase inhibitor like exemestane and. Letrozole has an average rating of 5. It works by decreasing the amount of estrogen produced by the body. When you eat carbohydrates, make them complex carbs (like whole grains and beans). Avoid alcohol as it may make you feel more tired and drowsy. Common letrozole side effects include hot flashes, nausea, and fatigue. Early-stage, hormone receptor–positive (HR+) breast cancer that has been treated. 4 years. Concerns. 5. Many cancers are hormone sensitive (estrogen or progesterone receptor positive) and their growth can be affected by lowering estrogen levels in the body. Medicines, such as naproxen and ibuprofen, are available to help manage bone and joint pain. It may also be used when someone is premenopausal and having treatment to stop the ovaries working (temporary menopause). 2 out of 10 from a total of 105 reviews for the treatment of Breast Cancer. 5 mg 30’s is used in the treatment of breast cancer in postmenopausal women. 1. Hot flushes can sometimes occur. signs of infection (e. Letrozole may be used with intracytoplasmic sperm injection cycles, particularly as a successful means of delivering in vitro fertilization care at an affordable price . . Avoid alcohol as it may make you feel more tired and drowsy. Letrozole is a prescription drug is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Whenever possible, give letrozole to yourself and follow the steps below. 5 mg once daily for a planned duration of 5 years; discontinue at relapse. Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. Letrozole lowers the levels of the female sex hormone oestrogen in the body. This activity will highlight the mechanism of action,. Although not FDA approved as a fertility medication, letrozole is one of the first choices for. Letrozole (Femara) can cause fatigue, dizziness, and sleepiness. Letrozole is not a drug that is used recreationally or abused. 1 Bone Effects. 60 for placebo and letrozole, respectively; P = . 5 Tablet is used in the treatment of Breast cancer,Infertility due to anovulation. Cases exposed to high dose letrozole 10 mg day −1 resulted in a higher ectopic pregnancy resolution rate of 85% (17/20), while the resolution rate of the low dose letrozole-treated group (5 mg day −1) was 65% (13/20), and also showed a significant reduction in β-hCG levels on the 11th day, 25. 3 Use in Extended Adjuvant Treatment of Early Breast Cancer. Moreover, the co-administration of gonadotropin and letrozole enhances outcomes in normal responders going through IVF cycles (13-15). uses. com. 0 yrs old Female asked about Letrozole use, 4 doctors answered this and 268 people found it useful. Post Views: 3,192. Lez-T tablets uses and price in Pakistan. Medical information for PMS-Letrozole including its dosage, uses, side, effects, interactions, pictures and warnings. Countries. It belongs to a group of medicines called aromatase inhibitors. It is available on prescription only. pain in the chest, groin, or legs, especially the calves. Letrozole. Call your doctor for medical advice. 5mg. is based on data of another medicine with exactly the same composition as the Cipla-Letrozole. Written by ASHP. If this occurs, take your tablets at bedtime. There were also twice as many cardiac deaths with letrozole than with tamoxifen (13 vs. comLetrozole is a medication used in the treatment of certain breast cancers. Letrozole is an oral aromatase inhibitor which has been approved by the FDA 8. It may be done with or without fertility drugs. Letrozole is a hormone therapy drug used to treat breast cancer in women who've gone through a natural menopause (when periods stop). (Day 1 is the first day of full flow). 2. hot flashes, warmth or redness in your face or chest; headache, dizziness, weakness; bone pain, muscle or joint pain; swelling, weight gain; increased sweating; or. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. IUI costs between $300 and $1,000 per try, and the chances of getting pregnant each cycle are just 15% to 20%, even when there are no fertility issues involved. massage. Got prescribed the letrozole on the smallest dose (2. 12+ months is a very long time to be continuing letrozole with no success. How does Letrozole work? It kills cancer cells. Fortunately, it is possible to become pregnant with PCOS. This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Hot flashes and night sweats. 1) Extended adjuvant treatment of postmenopausal women with early breast cancer who have received prior standard adjuvant tamoxifen therapy. IVF costs an average of $12,000 to. Letrozole uses. Results of a safety study to evaluate safety in the adjuvant setting comparing the effect on lumbar spine (L2-L4) BMD of adjuvant treatment with letrozole to that with tamoxifen showed at 24 months a median decrease in lumbar spine BMD of 4. The product code (s) for this leaflet is: PL 31750/0041 . In a randomized controlled trial, Al-Fadhli et al found that the pregnancy rate was significantly higher in patients with unexplained infertility treated with 5 mg/day compared with. Lesbians are kinkier and druggier. Some breast cancers are made to grow faster by a natural hormone called estrogen. 1% vs 17%; P <. Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. • Letrozole (LET-roe-zole) is a drug that is used to treat breast cancer. There is no evidence that the exposure of the oocytes to letrozole increases congenital defects at birth. Letrozole and Timed Intercourse for PCOS. Consideration should be given to monitoring BMD. Letrozole (Femara) is one of the first choice options for breast cancer that helps improve survival rates, but it is used only in women who've already. 1 Bone Effects. You usually take letrozole once a day – try. Call your doctor for medical advice about side effects. This drug has been used for this purpose for decades and is still one of the few drugs that provide guaranteed results. Lesbian-specific success rates for each treatment are explained along with risks. 5’ on other side. 6 vs. Letrozole blocks the conversion of C-19 androgens to C-18 estrogens by competitively inhibiting the enzyme, aromatase (cytochrome P-450 19), which is an essential step in estrogen biosynthesis in the ovary and other tissues. This drug has been available. For context, compared with IVF, IUI. (2018). Letrozole Tablets, USP are indicated for first-line treatment of postmenopausal women with hormone receptor positive or unknown, locally advanced or. 5 Tablet is used for Breast Cancer etc. 044) and a significant decrease in lumbar spine BMD (percentage change in T score, mean −0. Order Femara 2. In Menopausal Women, the Ovaries do not produce Estrogen. 5 mg orally once daily. Take with or without food. 000 in Brazil. Letrozole is used to treat breast cancer in postmenopausal women. These side effects can often be managed with lifestyle changes. Lezra tablet 2. Order Letrozone 2. 5mg (USP Specs) Price:…Abstract. 3%) had hypoestrogenic. Letrozole is approved to be used alone or with other drugs to treat: Breast cancer in postmenopausal women who have any of the following types of breast cancer--. 5. letrozole. Call your doctor for medical advice about side effects. Levalbuterol comes as a solution (liquid) to inhale by mouth using a nebulizer (machine that turns medication into a mist that can be inhaled), a concentrated solution to be mixed with normal saline and inhaled by mouth using a nebulizer, and as an aerosol to inhale by mouth using an inhaler. The results have been reported as Mean ± SD, frequencies and percentages. You may report side effects to the FDA at 1-800-332-1088. Lezra tablet contains Letrozole | belongs to Non-steroidal aromatase inhibitor. Hot flushes can sometimes occur. 5 mg once daily (453 patients) or tamoxifen. It works by blocking the effect of androgens. “Any time” includes follow-up period after completion or discontinuation of study treatment. Lezra is used to treat postmenopausal breast cancer. Consideration should be given to monitoring BMD. Advise pregnant women of the. What is letrozole used for? Letrozole is used to treat breast cancer in women after menopause (change of life). Filter by condition. ash hands with soap and water. ( 1. Complete Hemogram (CBC & ESR) Letzol 2. Prices vary from pharmacy to pharmacy. Bundred N, Campbell I, Coleman R, et al: Zoledronic acid in the prevention of cancer treatment-induced bone loss in postmenopausal women receiving letrozole as adjuvant therapy for early breast cancer (ZO-FAST study). Of these 19 boys, 17 (9 on T + Lz, 8 on T + Pl) completed the follow-up until near-final height, and constitute the population of the current study. This medication is used to treat certain types of breast cancer (such as hormone -receptor-positive breast cancer) in women after menopause. You are advised to take LETROZOLE for as long as your doctor has prescribed it for you depending on your medical condition. 5 Tablet (strip of 5 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. 008) at 24. 5 mg once daily. It is used for estrogen receptor-positive breast cancers [1, 2]. letrozole will increase the level or effect of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. In postmenopausal patients with breast cancer who received 2–3 years of tamoxifen, extended treatment with 5 years of letrozole resulted in a significant improvement in disease-free survival compared with the standard 2–3 years of letrozole. weight gain*. 1. fertnstert. (AJOG, 2021) assessed the impact of letrozole (an aromatase inhibitor) during frozen embryo transfer (FET) on obstetrical and perinatal outcomes of singleton and twin pregnancies compared with artificial cycle FET among women with polycystic ovary syndrome METHODS: Retrospective. Two studies, however, also used letrozole relatively close to the embryo transfer timing in fresh cycles with no reported adverse effects. Like all medications, letrozole can cause side effects. Non–Guideline-Supported Use Breast cancer, Neoadjuvant, postmenopausal, hormone receptor-positive. . 5 MG. It only works in women who are post-menopausal and producing estrogen outside the ovaries. Letrozole is a potent and selective aromatase inhibitor that inhibits intracellular aromatase activity. Alternate brands of Lezra tablet 2. Know Letroz 2. Based on our results, it is advisable to evaluate serum lipid levels every 3 months during the initial 6 months of AI treatment, and thereafter after. Weight gain or loss. Nice, France, March 21–25 (2006) (Abstract 12). The dosage usually lasts for 5 days to a week, if a tablet is taken every day. Be careful and be sure to specify the information on the section Name of the medicinal product in the instructions to the drug Cipla-Letrozole directly from the. Letrozole is also used to help prevent the cancer from returning. The incidence of vertebral deformation in children with idiopathic short stature increased after letrozole was used. In addition, in a study (AR/BC2) of 347 patients with advanced breast cancer, about half of whom received 2. Know it’s uses, side effects, reviews, composition and precautions only on 1mg. Some women will not respond to Clomid at all. itchiness. Letrozole decreases the amount of estrogen. This is a decision. Letrozole is also used to induce ovulation in women who exhibit polycystic ovary syndrome or anovulation. It aids in the adjuvant,. Common side effects of Letrozole mimic menopause symptoms and include hot flushes, difficulty sleeping, tiredness and low mood. Complete Hemogram (CBC & ESR) Letroz Tablet is used in the treatment of Breast cancer,Infertility due to anovulation. Therefore, letrozole treatment is considered an effective option in endometrial preparation for FET in patients with ovulation disorders or irregular menstruation. Nonmicronized T, letrozole, and stearic acid powders were mixed by mechanical means in a geometric ratio of 15:1:1. found. Letrozole comes in 2. Lesbian-specific success rates for each treatment are explained along with risks. Typical dosage. 5 mg tablet administered once a. 5 mg tablet administered once a day, without regard to meals. Novartis, the company responsible for the production of Femara (letrozole) does not recommend the use of this drug as an inducer of ovulation. Patients can take letrozole by mouth. The high suppression of estradiol reached in this study is similar to the results published in the literature [ 9 , 19 ]. It resists the spread of cancer to other areas of the body. 32% of reviewers reported a positive experience, while 34% reported a negative experience. Discontinuations for adverse reactions other than progression of tumor occurred in 10/455 (2%) of patients on Femara and in 15/455 (3%) of patients on tamoxifen. Intrauterine insemination (IUI) is a commonly used method of assisted reproduction for patients with mild male factor infertility,. 100). Results of a safety study to evaluate safety in the adjuvant setting comparing the effect on lumbar spine (L2 to L4) BMD of adjuvant treatment with letrozole to that with tamoxifen showed at 24 months a median. For this study, infertile women were recruited who were 40 years old or older. 014 46. In post-marketing reports, use of letrozole during pregnancy resulted in cases of spontaneous abortions and congenital birth defects. Lezole 2. May 29, 2022. Its anti-estrogen effect. When compared to megestrol, lower weight gain and vaginal bleeding have been observed with letrozole, but higher incidences of hot flashes, headache, rash, nausea, musculoskeletal pain, other. 2 Extended Adjuvant Treatment of Early Breast Cancer Femara is indicated for the extended adjuvant treatment of early breast cancer in postmenopausal women, who have received 5 years of adjuvant tamoxifen. Hair loss. In this video i am telling about lezra tablet. Order Letroz 2. 0) Other: 5 (3. If a woman does have a regular cycle, she can start medications on either day 3 or day 5 following the start of bleeding. Objective: The object of this study was to evaluate the efficacy of letrozole co-treatment with GnRH-antagonist protocol in ovarian stimulation of poor responder patients undergoing intracytoplasmic sperm injection. sudden loss of coordination. Letrozole 2. Letrozole should be taken anywhere from Day 2 to Day 5 of your menstrual cycle. There were no significant. According to the most recent research, letrozole can be used as the first-line therapy to treat infertility caused by polycystic ovarian syndrome and other causes. Adult: In hormone receptor +ve postmenopausal women: 2. Letrozole also enhances intrafollicular androgen. 5mg tablet is composed of Letrozole (2. A previous study reported that the use of the natural cycles for timing FETs should be reserved for younger patients, probably because the luteal phase defects are more common in patients with advanced maternal age . Letrozole is typically used in postmenopausal women who have already undergone other treatments for breast cancer. There have been a few cases of aromatase inhibitor induced vasculitis but the first case of letrozole-induced vasculitis was reported from Switzerland in 2014 (Digklia et al. Femara strength. Some of the most common ones include hot flashes, joint pain, fatigue, hair thinning, and nausea. Letrozole inhibits the production of Estrogen and thus prevents the growth of a Tumor. 97 kg were used for the study. Cytostatic. Student T-test and Fisher's Exact Test were used for quantitative variables and Chi-square was used for qualitative variables. Additionally, a study found that letrozole co-treatment could improve pregnancy outcomes by reversing the expression of anb3 integrin in the endometrium . Letrozole Teva reduces the amount of estrogen by blocking an. Femara may be used to treat postmenopausal women whose cancers are fueled by hormones. Explore New Perspectives. It is on the World. Letrozole works by blocking the action of the enzyme aromatase, which prevents the body from converting androgens into estrogens. As breast tissue is stimulated by estrogens, decreasing their production is a way of suppressing recurrence. 5 MG Tablet is a medicine used in the treatment of breast cancer in postmenopausal women (women who have not had periods for more than a year marking the end of menstrual cycles). Drowsiness/dizziness: Letrozole may cause dizziness or drowsiness. For oral dosage form (tablets): For breast cancer: Adults—2. 1. The recommended dose is one 2. Usage Instructions for Letrozole; Take this drug at the same time of day. com. This medicine is available only with your doctor's prescription. 688 of 1425 treatment cycles [48. 4%, p = 0. It was patented in 1986 and approved for medical use in 1996. Welch t-test was used because the variances between groups was not equal; * p < 0. Little is known, however, whether the use of letrozole during FET cycles (L-FET) could benefit the. 33) and natural cycle (OR 1. Common Femara side effects may include: hot flashes, warmth or redness in your face or chest; headache, dizziness, weakness; bone pain, muscle or joint pain; swelling, weight gain; increased sweating; or. Follicular development can be induced by the administration of letrozole via suppressing androgen conversion into oestradiol and increasing serum gonadotropin-releasing hormone levels []. 5 Tablet (strip of 10 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. Treatment may be continued up to 5 yr for extended adjuvant therapy or until tumour progression for. If you eat sweets or a high. increased cholesterol in your blood. Letrozole (LE) is a drug commonly used to induce ovulation. In light of the accumulating clinical. If estrogen is used, prescribe the lowest dose to relieve symptoms, monitor patient carefully and consider short term use. Besides, no obvious discomforts were found in group B patients during pre-HIFU medication, and three of group C patients (27. Letrozole is an aromatase inhibitor. Have a regular-ish long cycle (35-40 days) with sporadic late ovulation on day 22 ish. It belongs to a group of medicines called aromatase inhibitors. Due to the promising preclinical and phase 1 results, and once again to shorten development. Letrozole, an aromatase inhibitor, is a commonly used neo-adjuvant drug to treat hormone-sensitive breast cancer. com. Letrozole Uses . Because fatigue, dizziness, and somnolence have been reported with the use of letrozole, caution is advised when driving or using machinery until it is known how the patient reacts to letrozole use. 29 compared to the low dose. Letrozole inhibits the liver enzyme CYP2A6, and to a lesser extent CYP2C19, in vitro, but no relevant interactions with drugs like cimetidine and warfarin have been observed. Day 17 (Lønning et al. It can also be given as a sequential treatment; 2 years of Letrozole followed by 3 years of tamoxifen. They’re commonly prescribed for people with polycystic ovary syndrome (PCOS) or unexplained infertility. . But this combination can potentially cause rare adverse effects in the body, including kidney toxicity [95]. Letrozole Stada reduces the amount of estrogen by blocking an. Letrozole Tablets: Uses, Dosage, Side effects and Interactions Overview What is Letrozole? Letrozole, also known by the brand name Femara, is a non-steroidal aromatase inhibitor medicine1Overview| Researched based DrCure. The use of letrozole for ovulation induction in our clinic, and essentially worldwide, stopped as a result of the Novartis letter. Introduction. How does Letrozole (Femara) work? Letrozole is commonly prescribed to treat conditions impacted by estrogen levels, such as certain types of breast cancer. In patients with advanced disease, treatment with Letrozole Tablet should be continued until tumor progression is evident. com. 5 mg Tablets - NUTERENO HEALTH CARE You should only take Lez-T under strict medical supervision. It works by lowering the amount of estrogen the body produces. 21. Letrozole tablets, USP are indicated for the adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. Letrozole is used to treat breast cancer in postmenopausal women. In animal models of breast cancer, acquired resistance to letrozole can be reversed by discontinuing treatment, suggesting a strategy of alternating “on-off” letrozole treatment as a therapeutic option to prolong sensitivity to endocrine therapy. Home. Letrozole is a nonsteroidal aromatase inhibitor that reversibly binds to aromatase enzyme, and inhibits estrogen synthesis. Aromasin is a brand-name prescription medication. Introduction For Lezra Excel 2. In the BIG 1–98 trial, 2. Letrozole Tamoxifen; It is also known as Femara, an aromatase inhibitor used in the treatment of hormonally-responsive breast cancer following surgery. Background Polycystic ovary syndrome (PCOS) is a common cause of anovulatory infertility. As there are reports of women regaining ovarian function during treatment with letrozole despite a clear postmenopausal status at start of therapy, the physician needs to discuss adequate contraception when. Aromatase inhibitors have been used to prevent androgens from being converted to estrogen, thereby increasing testosterone in. 5 mg are dark yellow coloured, round, biconvex, film coated tablets with ‘LET’ debossed on one side and ‘2. Check with your doctor immediately if any of the following side effects occur: chills, fever, or flu-like symptoms. By 10 p. Letrozole isThose receiving letrozole had a significantly greater decrease in total hip BMD (percentage change in T score, mean −0. vaginal bleeding. Letrozole caused embryo-fetal toxicities in rats and rabbits at maternal exposures that were below the maximum recommended human dose (MHRD) on a mg/m 2 basis. Group 2- received gonadotropins alone. So, your ovaries produce more. 5 Tablet (strip of 5 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. 0 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg. Heart disease: This medication may increase the risk of heart attack or increased blood pressure. It is not associated with physical dependence or withdrawal. My follicles showed zero progress at 12mm so doc had me up my dosage to 5mg of Letrozole (thankfully without having to re-start my cycle). An alternative schedule of extended adjuvant endocrine therapy with letrozole, including intermittent administration, might be feasible and the. 5 mg Tablet. 1 Bone Effects. Letrozole. Clomid and Letrozole have emerged as go-to options for individuals seeking effective PCT strategies. Background: Aromatase inhibitors (AIs) have been used in boys with idiopathic short stature (ISS) to promote growth despite the lack of actual data regarding treatment effect on adult height. siponimod and letrozole both increase immunosuppressive effects; risk of infection. It sounds like your OB isn’t monitoring you. The relative potential for letrozole, anastrozole, and fadrozole has been assessed in a range of cellular endocrine and tumor systems containing aromatase ( 6). 1) Extended adjuvant treatment of postmenopausal women with early breast cancer who have received prior standard adjuvant tamoxifen therapy. swollen glands. Results of a substudy to evaluate safety in the adjuvant setting comparing the effect on lumbar spine (L2-L4) bone mineral density (BMD) of adjuvant treatment with letrozole to that with tamoxifen showed at 24 months a. Letrozole Teva contains an active substance called letrozole. Previous trials have shown bisphosphonates might help lower the risk of developing breast cancer in postmenopausal women and reduce recurrence and death in early stage breast cancer patients. Femara has sometimes been used in these women as an alternative to clomiphene. Advise pregnant women of the. vision changes. Cytostatic. dizziness or lightheadedness. Leave letrozole in the provided packaging until it is ready to be taken. Letrozole blocks the synthesis of estrogen in ovarian granulosa cells, resulting in reduced levels of circulating and intraovarian estrogens and increased levels of intraovarian androgens (Velasco and. At surgery, 23 (46·9%; 95% CI 32·5-61·7) of 49 patients in the ribociclib plus letrozole group and 24 (46·1%; 32·9-61·5) of 52 patients in the chemotherapy group were low-ROR. The growth of breast tumors is often stimulated by the female sex hormone estrogen. Skin-related adverse events associated with anastrozole inhibitor use are uncommon [3–18]. It has been more than 20 years since the initial clinical trial of letrozole for ovulation induction. Side effects of Femara and Clomid that are similar include nausea, vomiting, headache, and muscle aches or pains. Letroz 2. Always take letrozole exactly as your doctor has told you. Composition: Lezra excel contains 2. 16.